Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50015630
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587911(CHEMBL5183049)
Affinity DataKi:  9.46E+4nMAssay Description:Binding affinity to human recombinant COX-2 assessed as inhibition constant preincubated for 5 mins followed by arachidonic acid addition measured ev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587908(CHEMBL5193790)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587909(CHEMBL5174073)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587913(CHEMBL5174387)
Affinity DataIC50:  37nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  43nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587914(CHEMBL5200917)
Affinity DataIC50:  110nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  160nMAssay Description:Inhibition of ovine COX-2 by colorimetric inhibitor screening assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587915(CHEMBL5196989)
Affinity DataIC50:  170nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587910(CHEMBL5195593)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant EGFR (unknown origin) expressed in baculovirus incubated for 10 mins by europium-labeled antiphosphotyrosine/enhancement so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Ovis aries)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587916(CHEMBL5198027)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ovine COX-2 by colorimetric inhibitor screening assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587912(CHEMBL5202840)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of ovine COX-1 preincubated for 10 mins followed by arachidonic acid addition for 2 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587907(CHEMBL5175372)
Affinity DataIC50:  6.54E+4nMAssay Description:Inhibition of soybean LOX-1 using linoleic acid as substrate measured for 3 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587912(CHEMBL5202840)
Affinity DataIC50:  3.00E+6nMAssay Description:Inhibition of human recombinant COX-2 preincubated for 10 mins followed by arachidonic acid addition for 2 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed