Found 68 Enz. Inhib. hit(s) with all data for entry = 50018286 
Affinity DataIC50: 0.170nMAssay Description:Relative binding affinity for human estrogen receptor alpha by displacement of [3H]-estradiolMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.510nMAssay Description:Affinity against melatonin receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at rat GnRH receptor assessed as luteinizing hormone release in rat pituitary cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Concentration required to inhibit the HIV-1 recombinant Reverse Transcriptase (rRT) activity by 50%. Activated calf thymus DNA was used as template p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Concentration required to inhibit the HIV-1 recombinant Reverse Transcriptase (rRT) activity by 50%. Activated calf thymus DNA was used as template p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Concentration required to inhibit the HIV-1 recombinant Reverse Transcriptase (rRT) activity by 50%. Activated calf thymus DNA was used as template p...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 14nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Antagonist activity in phenoxybenzamine-treated rat by Pressor assayMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Affinity against melatonin receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Relative binding affinity for sheep uterine estrogen receptor by displacement of [3H]estradiolMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of P-glycoprotein expressed in MDCK-MDR1 cells by calcein AM assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))TBA
Affinity DataIC50: 48nMAssay Description:Relative binding affinity for human estrogen receptor beta by displacement of [3H]estradiolMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Binding affinity to DC-SIGN extracellular domain (unknown origin) expressed in Escherichia coli after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of P-glycoprotein expressed in MDCK-MDR1 cells by calcein AM assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of AChE in human erythrocytes using acetylthiocholine as substrate measured for 1 minMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of P-glycoprotein expressed in MDCK-MDR1 cells by calcein AM assayMore data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibition of P-glycoprotein expressed in MDCK-MDR1 cells by calcein AM assayMore data for this Ligand-Target Pair
Affinity DataIC50: 278nMAssay Description:Inhibition of P-glycoprotein expressed in MDCK-MDR1 cells by calcein AM assayMore data for this Ligand-Target Pair
Affinity DataIC50: 306nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Relative binding affinity for human estrogen receptor beta by displacement of [3H]estradiolMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 635nMAssay Description:Binding affinity to DC-SIGN extracellular domain (unknown origin) expressed in Escherichia coli after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Relative binding affinity for human estrogen receptor alpha by displacement of [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti...More data for this Ligand-Target Pair
Affinity DataIC50: 867nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
