Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50015658
TargetHistone deacetylase(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588303(CHEMBL5170036)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588302(CHEMBL5199116)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Rattus norvegicus)
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588304(CHEMBL5202398)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat HDAC1 using Boc-Lys(Ac)-AMC as substrate incubated for 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531348(CHEMBL4456028)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using AMC-K(Ac)GL as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  11nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531349(CHEMBL4451082)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  15nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588308(CHEMBL5204304)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588306(CHEMBL474318)
Affinity DataIC50:  30nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  36nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  47nMAssay Description:Inhibition of human HDAC2 expressed in HEK293T cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531334(CHEMBL472574)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531324(CHEMBL4468518)
Affinity DataIC50:  56nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588305(CHEMBL5209235)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531349(CHEMBL4451082)
Affinity DataIC50:  65nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531348(CHEMBL4456028)
Affinity DataIC50:  67nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50531324(CHEMBL4468518)
Affinity DataIC50:  83nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588309(CHEMBL470325)
Affinity DataIC50:  90nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  98nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50:  220nMAssay Description:Inhibition of HDAC1 in human MCF7 cells using TMB as substrate incubated for 2 hrs by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588307(CHEMBL451873)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588310(CHEMBL473512)
Affinity DataIC50:  330nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50:  430nMAssay Description:Inhibition of HDAC2 in human MCF7 cells using TMB as substrate incubated for 2 hrs by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  510nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588312(CHEMBL5203465)
Affinity DataIC50:  670nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588311(CHEMBL489280)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50048864(CHEMBL3310505)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human HDAC6 expressed in HEK293T cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTubulin beta-3 chain(Homo sapiens)
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588315(CHEMBL5197309)
Affinity DataIC50:  2.32E+3nMAssay Description:Inhibition of beta-tubulin polymerization in human MCF7 cells using TMB as substrate incubated for 2 hrs by spectrophotometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588314(CHEMBL4542499)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using AMC-K(Ac)GL as substrate by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50079401(CHEMBL62381 | Sodium butyrate | Sodium; butyrate |...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human recombinant His-tagged HDAC3 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50079401(CHEMBL62381 | Sodium butyrate | Sodium; butyrate |...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human recombinant full-length His-tagged HDAC2 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based ana...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50079401(CHEMBL62381 | Sodium butyrate | Sodium; butyrate |...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant His-tagged HDAC8 expressed in Escherichia coli incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50079401(CHEMBL62381 | Sodium butyrate | Sodium; butyrate |...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50588313(CHEMBL5179307)
Affinity DataIC50:  3.50E+5nMAssay Description:Inhibition of HDAC4 in human HeLa cells incubated for 1 hr by mass spectrometry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  7.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetHistone deacetylase 3(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  7.00E+5nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed