TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal GST-tagged HDAC6 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full-length recombinant human HDAC6 using RHKKAc peptide as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC6 (unknown origin) using acetyl-lysine tripeptide substrate as substrate preincubated for 24 hrs followed by substrate addition by ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of N-terminal GST-tagged HDAC6 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human HDAC6 using RHKKAc peptide as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human HDAC6 using fluorescent substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human HDAC6 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of N-terminal GST-tagged HDAC1 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of PDE9 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Inhibition of N-terminal GST-tagged HDAC2 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of N-terminal GST-tagged HDAC3 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 593nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 854nMAssay Description:Inhibition of recombinant human HDAC8 using RHKAcKAc peptide as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of HDAC7 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human HDAC4 using fluorescent substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of N-terminal GST-tagged HDAC1 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of N-terminal GST-tagged HDAC2 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human HDAC8 using fluorescent substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human HDAC1 using fluorescent substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human HDAC10 using fluorescent substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of recombinant human HDAC1 using RHKKAc peptide as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of full-length recombinant human HDAC9 using Boc-Lys(trifluoroacetyl)-AMC peptide as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of recombinant human HDAC2 using RHKKAc peptide as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of full-length recombinant human HDAC8 using RHKAcKAc peptide as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of full-length recombinant human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC peptide as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human HDAC2 using fluorescent substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of full-length recombinant human HDAC7 using Boc-Lys(trifluoroacetyl)-AMC peptide as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant human HDAC7 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibition of recombinant human HDAC3/NcoR2 using RHKKAc peptide as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC5 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant human HDAC9 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of full-length recombinant human HDAC1 using RHKKAc peptide as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 5.72E+3nMAssay Description:Inhibition of full-length recombinant human HDAC11 using Boc-Lys(trifluoroacetyl)-AMC peptide as substrate by fluorescence based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant human HDAC8 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC1 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC11 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC3 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC10 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC2 using fluorogenic substrateMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorescent peptide substrateMore data for this Ligand-Target Pair