Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of alpha7 nicotinic acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of alpha7 nicotinic acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair