Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50017769
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)
Affinity DataKi: <0.0100nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)
Affinity DataKi:  48nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-xL expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by flu...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  94nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human MCL-1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition const...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  100nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human BFL-1 (1 to 151 residues) expressed in Escherichia coli BL21 (DE3) assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)
Affinity DataKi:  245nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-W expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM34194(3-chloranyl-1-(3,4-dichlorophenyl)-4-(4-methylpipe...)
Affinity DataKi:  400nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human BFL-1 (1 to 151 residues) expressed in Escherichia coli BL21 (DE3) assessed...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi:  410nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)
Affinity DataKi: >444nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human MCL-1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition const...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50511138(CHEMBL4576854)
Affinity DataKi:  680nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604880(CHEMBL5191993)
Affinity DataKi:  1.13E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604882(CHEMBL5200494)
Affinity DataKi:  2.41E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604879(CHEMBL5187810)
Affinity DataKi:  2.85E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604877(CHEMBL5189912)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from His-tagged human BFL-1 (1 to 151 residues) expressed in Escherichia coli BL21 (DE3) assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604888(CHEMBL5172942)
Affinity DataKi:  3.01E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604895(CHEMBL5208811)
Affinity DataKi:  3.23E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604894(CHEMBL5207703)
Affinity DataKi:  3.34E+3nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604891(CHEMBL5196465)
Affinity DataKi:  1.02E+4nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM34194(3-chloranyl-1-(3,4-dichlorophenyl)-4-(4-methylpipe...)
Affinity DataKi:  1.25E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-like protein 2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM34194(3-chloranyl-1-(3,4-dichlorophenyl)-4-(4-methylpipe...)
Affinity DataKi:  1.25E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-W expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604877(CHEMBL5189912)
Affinity DataKi:  1.29E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604884(CHEMBL5180166)
Affinity DataKi:  1.81E+4nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604890(CHEMBL5192473)
Affinity DataKi:  1.84E+4nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604896(CHEMBL5188901)
Affinity DataKi:  2.41E+4nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM34194(3-chloranyl-1-(3,4-dichlorophenyl)-4-(4-methylpipe...)
Affinity DataKi:  5.00E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-xL expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by flu...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604893(CHEMBL5171576)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604892(CHEMBL5199717)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604889(CHEMBL5189196)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604886(CHEMBL5187123)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604883(CHEMBL5198914)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604881(CHEMBL5175046)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604887(CHEMBL5170736)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi:  1.11E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from human MCL-1 (172 to 327 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscriptional enhancer factor TEF-3(Homo sapiens)
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of FAM- labeled YAP1 peptide from TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetB-cell CLL/lymphoma 9 protein(Homo sapiens)
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of N-terminal biotinylated human BCL9 (350 to 375 residues)/C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of fluorescein tagged BAK peptide from N-terminal His tagged human BCL-xL (1 to 209 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of fluorescein tagged BIM peptide from N-terminal His tagged human BCL-2 (1 to 170 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTranscriptional enhancer factor TEF-4(Homo sapiens)
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of FAM- labeled YAP1 peptide from TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of biotinylated tagged PD-1 (unknown origin)/His tagged PD-L1 (unknown origin) protein-protein interaction assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of FAM- labeled PDI peptide from MDM2 (1 to 118 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Binding affinity to recombinant human BRD2 BD1 (72-205 residues) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Binding affinity to recombinant human BRD2 BD2 (349-460 residues) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Binding affinity to recombinant human BRD3 BD1 (24-144 residues) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKi: >4.00E+5nMAssay Description:Binding affinity to recombinant human BRD3 BD2 (306-417 residues) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604878(CHEMBL5206188)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of His-tagged human BFL-1(1 to 151 residues) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization-based binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBcl-2-related protein A1(Homo sapiens (Human))
Yancheng Teachers University

Curated by ChEMBL
LigandPNGBDBM50604885(CHEMBL5177177)
Affinity DataKd:  262nMAssay Description:Binding affinity to His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed