Found 47 Enz. Inhib. hit(s) with all data for entry = 50016452 TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by DTNB reagent...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of recombinant human AChE using Amplex red, acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 45 mins followed by substrate addition by DTNB reage...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human AChE using Amplex red, acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Inhibition of human BACE-1 using Rh-EVNLDAEFK-quencher as peptide substrate incubated for 1 hr in dark by FRET assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by El...More data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured for...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of NMDA receptor (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and m...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 615nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocholine chloride as substrate by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 30 mins followed by substrate addition and measured after 20 ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of FAAH (unknown origin) using 7-amino-4-methylcoumarin-arachidonamide as substrate preincubated for 5 mins followed by substrate addition...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant human MAO-B assessed as formation of 4-hydroxyquinoline using kynuramine as a substrate incubated for 30 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human BACE-1 using MCA-SEVNLDAEFR-Ednp-KRR-NH2.3TFA as substrate incubated for 2 hrs by Varioskan-flash multimode plate rea...More data for this Ligand-Target Pair
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition and measured for 12 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human MAO-A assessed as amount of 4-hydroxyquinoline using kynuramine as a substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human BACE-1 using rhodamine-EVNLDAEFK-quencher as peptide substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 6.77E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 8.07E+3nMAssay Description:Inhibition of self induced amyloid beta (1 to 42) (unknown origin) aggregation incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant human MAO-B assessed as amount of 4-hydroxyquinoline using kynuramine as a substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of BuChE (unknown origin) incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 9.26E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregation incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 9.91E+3nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of AChE (unknown origin) by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of Electrophorus electricus AchE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of BuChE (unknown origin) by spectrophotometric based Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human LOX-5 using arachidonic acid and ATP as substrate preincubated for 10 mins followed by substrate addition and measured after 20 m...More data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 4.91E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregation incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 3.38E+5nMAssay Description:Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.41E+5nMAssay Description:Inhibition of MMP-2 (unknown origin) by Fluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+6nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate preincubated for 20 mins followed by substrate addition by DTNB reage...More data for this Ligand-Target Pair
