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Found 14 Enz. Inhib. hit(s) with all data for entry = 50017859
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605545(CHEMBL5182175)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605545(CHEMBL5182175)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605545(CHEMBL5182175)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605545(CHEMBL5182175)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50396169(CHEMBL1337170)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of STAT3-SH2 (unknown origin) using 5-carboxyfluorescein-GY(PO3H2)EEIP as substrate incubated with compound for 1 hr followed by substrate...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605550(C-188-9 | Stat3 inhibitor c188-9 | Stat3 inhibitor...)
Affinity DataKd:  250nMAssay Description:Binding affinity to full length STAT3 (unknown origin) by Surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605545(CHEMBL5182175)
Affinity DataKd:  960nMAssay Description:Binding affinity to His-tagged STAT3-SH2 domain (586 to 685 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataKd:  500nMAssay Description:Binding affinity to full length STAT3 (unknown origin) by Surface plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605545(CHEMBL5182175)
Affinity DataKd:  460nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605548(CHEMBL5204232)
Affinity DataKd:  640nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605547(CHEMBL5178793)
Affinity DataKd:  360nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605546(CHEMBL5174100)
Affinity DataKd:  310nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataKd:  4.57E+3nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50605549(CHEMBL5175326)
Affinity DataKd:  590nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed