Found 21 Enz. Inhib. hit(s) with all data for entry = 50015896 Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 0.153nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT6 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity to human AChE assessed as inhibition constantMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity to sigma1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of equine serum BChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine as substrate incubated for 3 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 5.93E+3nMAssay Description:Inhibition of self-aggregation of amyloid beta (1 to 42) (unknown origin) by thioflavin T methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 60 mins by A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated polypeptide substrate measured after 30 mins in presence of ATP by Kinase-Glo Lumin...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of BACE-1 (unknown origin) using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lysdinitrophenyl as substrate preincubated for 1 hr f...More data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of human AChE-induced amyloid beta (1 to 40) aggregation (unknown origin)More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Guizhou Medical University
Curated by ChEMBL
Guizhou Medical University
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of recombinant human NLRP3 ATPase activity preincubated for 15 mins followed by ATP addition measured after 40 mins by ADP-Glo Kinase assa...More data for this Ligand-Target Pair
