Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 50035550
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025927(CHEMBL3143966 | {1-[1-[1-(2,2-Difluoro-2-{2-methyl...)
Affinity DataIC50:  0.520nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025928(CHEMBL57121 | {1-[1-[1-(1-Hydroxy-2-{2-methyl-1-[(...)
Affinity DataIC50:  1.70nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50:  10nMpH: 2.0Assay Description:Inhibitory activity was evaluated against pepsin using porcine pepsin (sigma), porcine hemoglobin (sigma) and 0.02 M KCl-HCl buffer (pH 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025930(CHEMBL427581 | {1-[1-[1-(2,2-Difluoro-1-hydroxy-2-...)
Affinity DataIC50:  12nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity was evaluated against bovine cathepsin D (sigma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025926((1-{2-(1H-Imidazol-4-yl)-1-[3-methyl-1-(2-{2-methy...)
Affinity DataIC50:  34nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025929(CHEMBL57399 | {1-[1-[1-(2,2-Difluoro-1-hydroxy-2-{...)
Affinity DataIC50:  730nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM912((3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-m...)
Affinity DataIC50:  6.00E+3nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  9.41E+3nMAssay Description:Plasma renin inhibitory activity was evaluated in lyophilized human plasma with 0.1%EDTAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022851(CHEMBL413534 | Pro-His-Pro-Phe-His-Phe-Phe-Val-Tyr...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity was evaluated against Angiotensin I converting enzyme activity in rabbitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed