Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50028983
TargetChymotrypsinogen A(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  2.50E+3nMAssay Description:Concentration required to inhibit the enzyme chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin S(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  4.00E+3nMAssay Description:Concentration required to inhibit the enzyme cathepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  4.00E+4nMAssay Description:Concentration required to inhibit the enzyme pepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  16nMAssay Description:Concentration of the compound required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  22nMAssay Description:Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH)More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280493(CHEMBL430077 | {(S)-1-[(S)-1-((S)-1-Cyclohexylmeth...)
Affinity DataIC50:  250nMAssay Description:Concentration of the compound required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280490((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50: >1.00E+3nMAssay Description:Concentration of the compound required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  3.00E+3nMAssay Description:Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280491((S)-6-(4-Methoxy-phenyl)-5-(3-methyl-butyrylamino)...)
Affinity DataIC50:  2.50E+4nMAssay Description:Concentration of the compound required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280494(CHEMBL545117 | N-[(S)-1-[(R)-1-((S)-4-Amino-1-cycl...)
Affinity DataIC50:  2.70E+4nMAssay Description:Concentration of the compound required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280492((S)-2-{[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyr...)
Affinity DataIC50:  4.00E+4nMAssay Description:Concentration of the compound required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  1.00E+5nMAssay Description:Concentration of the compound required to inhibit rat plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article