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Found 39 Enz. Inhib. hit(s) with all data for entry = 50029095
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281455(3-(2-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  1nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281459(9-Benzyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2-en...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281447(3-(4-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  4nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  4nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281453(9-Phenethyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2...)
Affinity DataKi:  5nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281450(3-(4-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  6nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281452(9-Phenethyl-3-thiophen-2-yl-1-oxa-9-aza-spiro[5.5]...)
Affinity DataKi:  7nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281454(9-Phenethyl-2-phenyl-1-oxa-9-aza-spiro[5.5]undec-2...)
Affinity DataKi:  10nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281451(8-Benzyl-3-phenyl-1-oxa-8-aza-spiro[5.5]undec-2-en...)
Affinity DataKi:  13nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281457(3-(4-Methoxy-phenyl)-9-phenethyl-1-oxa-9-aza-spiro...)
Affinity DataKi:  30nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281444(2-(3-Diethylamino-propyl)-2-methyl-5-phenyl-2,3-di...)
Affinity DataKi:  34nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  47nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281445(2-Furan-2-yl-9-phenethyl-1-oxa-9-aza-spiro[5.5]und...)
Affinity DataKi:  70nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281448(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[5.5...)
Affinity DataKi:  131nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281458(2-Dimethylaminomethyl-2-methyl-5-phenyl-2,3-dihydr...)
Affinity DataKi:  352nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281452(9-Phenethyl-3-thiophen-2-yl-1-oxa-9-aza-spiro[5.5]...)
Affinity DataKi:  1.08E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281459(9-Benzyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2-en...)
Affinity DataKi:  1.46E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281457(3-(4-Methoxy-phenyl)-9-phenethyl-1-oxa-9-aza-spiro...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281447(3-(4-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  1.53E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281461(5'-phenylspiro[4-azabicyclo[2.2.2]octane-2,2'-pyra...)
Affinity DataKi:  1.59E+3nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281449(8-methyl-5'-phenylspiro[8-azabicyclo[3.2.1]octane-...)
Affinity DataKi:  1.83E+3nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281453(9-Phenethyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2...)
Affinity DataKi:  2.03E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281455(3-(2-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  2.33E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281450(3-(4-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...)
Affinity DataKi:  2.90E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281458(2-Dimethylaminomethyl-2-methyl-5-phenyl-2,3-dihydr...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281454(9-Phenethyl-2-phenyl-1-oxa-9-aza-spiro[5.5]undec-2...)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281446(9-Methyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2-en...)
Affinity DataKi:  6.88E+3nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281460(3-(4-Fluoro-phenyl)-9-methyl-1-oxa-9-aza-spiro[5.5...)
Affinity DataKi:  7.30E+3nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281456(9-Benzyloxy-3-phenyl-1-oxa-spiro[5.5]undec-2-en-4-...)
Affinity DataKi:  7.50E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281445(2-Furan-2-yl-9-phenethyl-1-oxa-9-aza-spiro[5.5]und...)
Affinity DataKi:  7.60E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281448(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[5.5...)
Affinity DataKi:  8.78E+3nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281461(5'-phenylspiro[4-azabicyclo[2.2.2]octane-2,2'-pyra...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281444(2-(3-Diethylamino-propyl)-2-methyl-5-phenyl-2,3-di...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281456(9-Benzyloxy-3-phenyl-1-oxa-spiro[5.5]undec-2-en-4-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281456(9-Benzyloxy-3-phenyl-1-oxa-spiro[5.5]undec-2-en-4-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281456(9-Benzyloxy-3-phenyl-1-oxa-spiro[5.5]undec-2-en-4-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281449(8-methyl-5'-phenylspiro[8-azabicyclo[3.2.1]octane-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281446(9-Methyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2-en...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281460(3-(4-Fluoro-phenyl)-9-methyl-1-oxa-9-aza-spiro[5.5...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails Article