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Found 18 Enz. Inhib. hit(s) with all data for entry = 50029653
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286567((R)-2-[(S)-10-Amino-1-((S)-4-guanidino-1-phenylcar...)
Affinity DataKi:  110nMAssay Description:Inhibition of human gelatinase A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286566((R)-2-[(S)-1-((S)-4-Guanidino-1-phenylcarbamoyl-bu...)
Affinity DataKi:  120nMAssay Description:Inhibition of human gelatinase A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  200nMAssay Description:Inhibition of human gelatinase A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286565((R)-2-[(S)-10-Amino-1-((S)-3-methyl-1-phenylcarbam...)
Affinity DataKi:  240nMAssay Description:Inhibition of human fibroblast stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286568((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi:  340nMAssay Description:Inhibition of human gelatinase A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286567((R)-2-[(S)-10-Amino-1-((S)-4-guanidino-1-phenylcar...)
Affinity DataKi:  370nMAssay Description:Inhibition of human fibroblast stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  470nMAssay Description:Inhibition of human fibroblast stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286565((R)-2-[(S)-10-Amino-1-((S)-3-methyl-1-phenylcarbam...)
Affinity DataKi:  500nMAssay Description:Inhibition of human gelatinase A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286569((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi:  560nMAssay Description:Inhibition of human gelatinase A (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286568((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi:  570nMAssay Description:Inhibition of human fibroblast stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50057083((R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pe...)
Affinity DataKi:  760nMAssay Description:Inhibition of human fibroblast collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286569((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi:  850nMAssay Description:Inhibition of human fibroblast stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286566((R)-2-[(S)-1-((S)-4-Guanidino-1-phenylcarbamoyl-bu...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human fibroblast stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286568((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human fibroblast collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286569((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human fibroblast collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286565((R)-2-[(S)-10-Amino-1-((S)-3-methyl-1-phenylcarbam...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human fibroblast collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286566((R)-2-[(S)-1-((S)-4-Guanidino-1-phenylcarbamoyl-bu...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human fibroblast collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286567((R)-2-[(S)-10-Amino-1-((S)-4-guanidino-1-phenylcar...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human fibroblast collagenase (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article