Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50029733
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  1nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287383((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50:  1nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287378((R)-N*1*-[(S)-1-(1H-Benzoimidazol-2-yl)-3-methyl-b...)
Affinity DataIC50:  2nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287381((S)-2-Cyclohexyl-N*4*-hydroxy-N*1*-[(S)-3-methyl-1...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287380((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-(6-methoxy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287379(4-[(S)-2-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287378((R)-N*1*-[(S)-1-(1H-Benzoimidazol-2-yl)-3-methyl-b...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287385((R)-N*1*-[1-(1H-Benzoimidazol-2-yl)-2-(1H-indol-3-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287380((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-(6-methoxy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50:  10nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287386((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287386((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287385((R)-N*1*-[1-(1H-Benzoimidazol-2-yl)-2-(1H-indol-3-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287385((R)-N*1*-[1-(1H-Benzoimidazol-2-yl)-2-(1H-indol-3-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287378((R)-N*1*-[(S)-1-(1H-Benzoimidazol-2-yl)-3-methyl-b...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287380((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-(6-methoxy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50:  33nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287382(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  70nMAssay Description:Inhibition of matrilysin, matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287383((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50:  112nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287383((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287386((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-2-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287382(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287381((S)-2-Cyclohexyl-N*4*-hydroxy-N*1*-[(S)-3-methyl-1...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287382(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287381((S)-2-Cyclohexyl-N*4*-hydroxy-N*1*-[(S)-3-methyl-1...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails Article