Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50004969
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  0.700nMAssay Description:Inhibitory concentration of the compound against CCRF-CEM leukemic cell DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  6nMAssay Description:inhibitory concentration of the compound against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration of the compound against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)
Affinity DataIC50:  450nMAssay Description:Inhibitory concentration of the compound against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)
Affinity DataIC50:  560nMAssay Description:inhibitory concentration of the compound against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration of the compound against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50:  3.05E+4nMAssay Description:Inhibitory concentration of the compound against CCRF-CEM leukemic cell DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibitory concentration of the compound against recombinant human TS (Thymidylate synthase).More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030820((S)-2-(4-((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)me...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: >2.00E+5nMAssay Description:inhibitory concentration of the compound against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030819((S)-2-(4-(2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibitory concentration of the compound against recombinant human TS (Thymidylate synthase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed