Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50006494
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.560nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049805(CHEMBL169703 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049807(2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  1nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049805(CHEMBL169703 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50005463((R)-1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-...)
Affinity DataKi:  3.69nMAssay Description:Binding affinity against Cholecystokinin type B receptor using [3H](MeNLE28,31)-CCK-8 as radioligand in guinea pig cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049808(CHEMBL127968 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049807(2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049803(CHEMBL124015 | Thiophene-2-carboxylic acid [2-(7-c...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049809(CHEMBL126282 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi:  18nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049801(4-Chloro-N-[2-(7-chloro-1-methyl-5-phenyl-2,3-dihy...)
Affinity DataKi:  35nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049805(CHEMBL169703 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataKi:  47nMAssay Description:Binding affinity against Cholecystokinin type A receptor using [125I]-(BH)-CCK-8 as radioligand in rat pancreas.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049808(CHEMBL127968 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi:  53nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049809(CHEMBL126282 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi:  62nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049803(CHEMBL124015 | Thiophene-2-carboxylic acid [2-(7-c...)
Affinity DataKi:  69nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049801(4-Chloro-N-[2-(7-chloro-1-methyl-5-phenyl-2,3-dihy...)
Affinity DataKi: >100nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universitá

Curated by ChEMBL
LigandPNGBDBM50049804(1H-Indole-2-carboxylic acid [2-(7-chloro-1-methyl-...)
Affinity DataKi: >100nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  105nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Universitá

Curated by ChEMBL
LigandPNGBDBM50008170(4-(3,4-Dichloro-benzoylamino)-4-dipentylcarbamoyl-...)
Affinity DataKi:  129nMAssay Description:Binding affinity against Cholecystokinin type A receptor using [125I]-(BH)-CCK-8 as radioligand in rat pancreas.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049805(CHEMBL169703 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataKi:  153nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  275nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049804(1H-Indole-2-carboxylic acid [2-(7-chloro-1-methyl-...)
Affinity DataKi:  296nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049807(2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi: >300nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049808(CHEMBL127968 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049809(CHEMBL126282 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049803(CHEMBL124015 | Thiophene-2-carboxylic acid [2-(7-c...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049801(4-Chloro-N-[2-(7-chloro-1-methyl-5-phenyl-2,3-dihy...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against delta Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049804(1H-Indole-2-carboxylic acid [2-(7-chloro-1-methyl-...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against delta Opioid receptor delta 1 using [3H]-DADLE as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity against Cholecystokinin type B receptor using [3H](MeNLE28,31)-CCK-8 as radioligand in guinea pig cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049803(CHEMBL124015 | Thiophene-2-carboxylic acid [2-(7-c...)
Affinity DataKi:  1.70E+4nMAssay Description:Binding affinity against Cholecystokinin type B receptor using [3H](MeNLE28,31)-CCK-8 as radioligand in guinea pig cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50049805(CHEMBL169703 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity against Cholecystokinin type B receptor using [3H](MeNLE28,31)-CCK-8 as radioligand in guinea pig cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed