Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50036608
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  3.10E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  2.32E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  3.00E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 3 (mGluR3)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataEC50:  280nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  3.80E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  4.90E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  1.30E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  8.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.00E+3nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  330nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.40E+4nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004051(2-Amino-4-phosphono-butyric acid | 2-Amino-4-phosp...)
Affinity DataEC50:  330nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataEC50:  24nMAssay Description:Agonistic activity against Human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  8.00E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.60E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  290nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50004863((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...)
Affinity DataEC50:  5.00E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  4.90E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.30E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  8.20E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  1.50E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064247((1S,2S,4S,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  9.10E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  720nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  9.80E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.21E+5nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  2.30E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50056272((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...)
Affinity DataEC50:  5.10nMAssay Description:Agonistic activity against Human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064246((1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.70E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >3.00E+5nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  2.30E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064245((1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed