Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 50008250
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065407((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataIC50:  11nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071828(Benzenesulfonic acid (3R,5S)-1-benzenesulfonyl-5-(...)
Affinity DataIC50:  13nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071825((R)-1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxyli...)
Affinity DataIC50:  14nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071823((2R,4R)-4-Azido-1-(toluene-4-sulfonyl)-pyrrolidine...)
Affinity DataIC50:  28nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071828(Benzenesulfonic acid (3R,5S)-1-benzenesulfonyl-5-(...)
Affinity DataIC50:  38nMAssay Description:Compound was tested for inhibitory activity against Cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071829((S)-1-Benzenesulfonyl-pyrrolidine-2-carboxylic aci...)
Affinity DataIC50:  41nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065407((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataIC50:  42nMAssay Description:Compound was tested for inhibitory activity against Cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071827((S)-1-Methanesulfonyl-pyrrolidine-2-carboxylic aci...)
Affinity DataIC50:  45nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071826((R)-1-Methanesulfonyl-pyrrolidine-2-carboxylic aci...)
Affinity DataIC50:  53nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071824((2R,4R)-1-(Toluene-4-sulfonyl)-4-(2,2,2-trifluoro-...)
Affinity DataIC50:  100nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071830((2S,4R)-1-Benzenesulfonyl-4-benzyloxy-pyrrolidine-...)
Affinity DataIC50:  125nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071827((S)-1-Methanesulfonyl-pyrrolidine-2-carboxylic aci...)
Affinity DataIC50:  883nMAssay Description:Compound was tested for inhibitory activity against Cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071829((S)-1-Benzenesulfonyl-pyrrolidine-2-carboxylic aci...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was tested for inhibitory activity against Cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071826((R)-1-Methanesulfonyl-pyrrolidine-2-carboxylic aci...)
Affinity DataIC50:  3.00E+3nMAssay Description:Compound was tested for inhibitory activity against Cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071825((R)-1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxyli...)
Affinity DataIC50:  3.60E+3nMAssay Description:Compound was tested for inhibitory activity against Cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071822((2R,4R)-4-Cyano-1-(toluene-4-sulfonyl)-pyrrolidine...)
Affinity DataIC50:  8.70E+3nMAssay Description:Compound was tested for inhibitory activity against Cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071822((2R,4R)-4-Cyano-1-(toluene-4-sulfonyl)-pyrrolidine...)
Affinity DataIC50:  8.70E+3nMAssay Description:Compound was tested for inhibitory activity against recombinant human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50071823((2R,4R)-4-Azido-1-(toluene-4-sulfonyl)-pyrrolidine...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for inhibitory activity against Cathepsin B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed