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Found 25 Enz. Inhib. hit(s) with all data for entry = 10891
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576415((R)-2-(1-Cyclopropyl-2-hydroxy-2-methylpropyl)-7-(...)
Affinity DataEC50:  7.90nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576439(WO2022115301, Example 25)
Affinity DataEC50:  9.20nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576417((R)-2-(1-Cyclopropyl-2-hydroxy-2-methylpropyl)-5-f...)
Affinity DataEC50:  2nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576418((R and S)- (E)-2-(1-cyclopropyl-2-hydroxy-2-methyl...)
Affinity DataEC50:  290nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576419(WO2022115301, Example 5)
Affinity DataEC50:  52nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576420(WO2022115301, Example 6)
Affinity DataEC50:  4.5nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576421(WO2022115301, Example 7)
Affinity DataEC50:  3.60nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576422(WO2022115301, Example 8)
Affinity DataEC50:  7.5nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576423(WO2022115301, Example 9)
Affinity DataEC50:  24nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576424(WO2022115301, Example 10)
Affinity DataEC50:  2.80nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576425(WO2022115301, Example 11)
Affinity DataEC50:  4.90nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576426(WO2022115301, Example 12)
Affinity DataEC50:  13nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576427(WO2022115301, Example 13)
Affinity DataEC50:  260nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576428(WO2022115301, Example 14)
Affinity DataEC50:  48nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576429(WO2022115301, Example 15)
Affinity DataEC50:  6.40nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576430(WO2022115301, Example 16)
Affinity DataEC50:  39nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576431(WO2022115301, Example 17)
Affinity DataEC50:  580nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576432(WO2022115301, Example 18)
Affinity DataEC50:  45nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576433(WO2022115301, Example 19)
Affinity DataEC50:  28nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576434(WO2022115301, Example 20)
Affinity DataEC50:  67nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576435(WO2022115301, Example 21)
Affinity DataEC50:  0.910nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576436(WO2022115301, Example 22)
Affinity DataEC50:  6.90nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576437(WO2022115301, Example 23)
Affinity DataEC50:  0.410nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576438(WO2022115301, Example 24)
Affinity DataEC50:  0.930nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576416((R or S)-2-(1-Cyclopropyl-2-hydroxy-2-methylpropyl...)
Affinity DataEC50:  2.60nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed