Reaction Details
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Report a problem with these dataTarget
Thromboxane A2 receptor
Ligand
BDBM50090136
Substrate
n/a
Ki
770±n/a nM
Comments
PDSP_4873
Citation
Armstrong, RA; Jones, RL; Wilson, NH Ligand binding to thromboxane receptors on human platelets: correlation with biological activity. Br J Pharmacol 79:953-64 (1983) [PubMed] Article More Info.:
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_MOUSE | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37114.77
Organism:
MOUSE
Description:
Thromboxane A2 TBXA2R MOUSE::P30987
Residue:
341
Sequence:
MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP
Inhibitor
Name:
BDBM50090136
Synonyms:
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hydroxy-4,4-dimethyl-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid | 16,16-dimethyl PGF2alpha | 7-[(1R,2R,4S,5R)-3,5-Dihydroxy-2-((E)-(R)-3-hydroxy-4,4-dimethyl-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid | CHEMBL40183
Type:
Small organic molecule
Emp. Form.:
C22H38O5
Mol. Mass.:
382.5341
SMILES:
CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Structure:
