Target
Genome polyprotein
Ligand
BDBM10303
Substrate
n/a
Meas. Tech.
ChEMBL_393 (CHEMBL615643)
Ki
51000±n/a nM
Citation
 Webber, SETikhe, JWorland, STFuhrman, SAHendrickson, TFMatthews, DALove, RAPatick, AKMeador, JWFerre, RABrown, ELDeLisle, DMFord, CEBinford, SL Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease. J Med Chem 39:5072-82 (1997) [PubMed]  Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM10303
Synonyms:
1-methyl-2,3-dioxo-2,3-dihydro-1H-indole-5-carbonitrile | CHEMBL64584 | Isatin analog 7
Type:
Small organic molecule
Emp. Form.:
C10H6N2O2
Mol. Mass.:
186.1668
SMILES:
CN1C(=O)C(=O)c2cc(ccc12)C#N
Structure:
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