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Target
D(2) dopamine receptor
Ligand
BDBM50084487
Substrate
n/a
Meas. Tech.
ChEMBL_61628 (CHEMBL673084)
Ki
3170±n/a nM
Citation
 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V A structure-affinity relationship study on derivatives of N-[2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a high-affinity and selective D(4) receptor ligand. J Med Chem 43:270-7 (2000) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50084487
Synonyms:
2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-5-methoxy-3,4-dihydro-2H-isoquinolin-1-one (2HCL .3/2H2O) | CHEMBL96799
Type:
Small organic molecule
Emp. Form.:
C22H26ClN3O2
Mol. Mass.:
399.914
SMILES:
COc1cccc2C(=O)N(CCN3CCN(CC3)c3ccc(Cl)cc3)CCc12
Structure:
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