Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50092738
Substrate
n/a
Meas. Tech.
ChEMBL_202060 (CHEMBL813143)
Ki
2350±n/a nM
Citation
 Eisenhut, M; Hull, WE; Mohammed, A; Mier, W; Lay, D; Just, W; Gorgas, K; Lehmann, WD; Haberkorn, U Radioiodinated N-(2-diethylaminoethyl)benzamide derivatives with high melanoma uptake: structure-affinity relationships, metabolic fate, and intracellular localization. J Med Chem 43:3913-22 (2000) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50092738
Synonyms:
4-Amino-5-bromo-N-(2-diethylamino-ethyl)-3-iodo-2-methoxy-benzamide | CHEMBL126723
Type:
Small organic molecule
Emp. Form.:
C14H21BrIN3O2
Mol. Mass.:
470.144
SMILES:
CCN(CC)CCNC(=O)c1cc(Br)c(N)c(I)c1OC
Structure:
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