Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50561600
Substrate
n/a
Meas. Tech.
ChEMBL_2075497 (CHEMBL4731031)
Ki
85±n/a nM
Citation
 Tosh, DK; Salmaso, V; Rao, H; Campbell, R; Bitant, A; Gao, ZG; Auchampach, JA; Jacobson, KA Direct Comparison of (N)-Methanocarba and Ribose-Containing 2-Arylalkynyladenosine Derivatives as A ACS Med Chem Lett 11:1935-1941 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3AR | AA3R_MOUSE | Adenosine A3 receptor | Adora3 | Gpcr2
Type:
PROTEIN
Mol. Mass.:
36460.91
Organism:
Mus musculus
Description:
ChEMBL_1515686
Residue:
319
Sequence:
MEADNTTETDWLNITYITMEAAIGLCAVVGNMLVIWVVKLNPTLRTTTVYFIVSLALADIAVGVLVIPLAIAVSLQVKMHFYACLFMSCVLLIFTHASIMSLLAIAVHRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKATLASSQNSSTLLCHFRSVVSLDYMVFFSFITWILVPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFDVKIPDVAMCLGILLSHANSMMNPIVYACKIKKFKETYFLILRAVRLCQTSDSLDSNMEQTTE
  
Inhibitor
Name:
BDBM50561600
Synonyms:
CHEMBL4788488
Type:
Small organic molecule
Emp. Form.:
C20H19FN6O3S
Mol. Mass.:
442.467
SMILES:
[H][C@]12C[C@]1([C@@H](O)[C@@H](O)[C@@H]2n1cnc2c(NC)nc(nc12)C#Cc1ccc(F)s1)C(=O)NC |r|
Structure:
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