Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 2
Ligand
BDBM50565184
Substrate
n/a
Meas. Tech.
ChEMBL_2091000 (CHEMBL4772263)
Ki
282±n/a nM
Citation
 Nguyen, T; Marusich, J; Li, JX; Zhang, Y Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. J Med Chem 63:12387-12402 (2020) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 2
Synonyms:
G-protein coupled receptor 74 | Gpr74 | NPFF2_RAT | Neuropeptide G-protein coupled receptor | Npff2 | Npffr2 | Npgpr
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47725.66
Organism:
RAT
Description:
NPFF2 0 RAT::Q9EQD2
Residue:
417
Sequence:
MGKRWDSNSSGSWDHIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCMVGNTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTSAHSTGKQRLEQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYADLSPNKLRVINIYVYPFAHWLAFCNSSVNPIIYGFFNENFRSGFQDAFQFCQKKVKPQEAYGLRAKRNLDINTSGLLVHEPASQNPSGENLGCRKSADNPTQESLMEETGEATNSTET
  
Inhibitor
Name:
BDBM50565184
Synonyms:
CHEMBL4799458
Type:
Small organic molecule
Emp. Form.:
C11H11ClN4
Mol. Mass.:
234.685
SMILES:
Cc1cc(NC(N)=N)nc2ccc(Cl)cc12
Structure:
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