Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 1
Ligand
BDBM50565193
Substrate
n/a
Meas. Tech.
ChEMBL_2091020 (CHEMBL4772283)
Ki
610±n/a nM
Citation
 Nguyen, T; Marusich, J; Li, JX; Zhang, Y Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. J Med Chem 63:12387-12402 (2020) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 1
Synonyms:
G-protein coupled receptor 147 | GPR147 | NPFF1 | NPFF1_HUMAN | NPFFR1 | RFamide-related peptide receptor OT7T022
Type:
PROTEIN
Mol. Mass.:
47840.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1474637
Residue:
430
Sequence:
MEGEPSQPPNSSWPLSQNGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSDSGLPSESGPSSGAPRPGRLPLRNGRVAHHGLPREGPGCSHLPLTIPAWDI
  
Inhibitor
Name:
BDBM50565193
Synonyms:
CHEMBL4780551
Type:
Small organic molecule
Emp. Form.:
C28H30ClN3O5
Mol. Mass.:
524.008
SMILES:
COc1ccc(CN[C@H]2C[C@H](N(Cc3ccccc3Cl)C2)C(=O)OCCc2ccc(cc2)[N+]([O-])=O)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: