Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50570988
Substrate
n/a
Meas. Tech.
ChEMBL_2113527 (CHEMBL4822377)
Ki
487±n/a nM
Citation
 Buabeng, ER; Henary, M Developments of small molecules as inhibitors for carbonic anhydrase isoforms. Bioorg Med Chem 39:0 (2021) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50570988
Synonyms:
CHEMBL4863803
Type:
Small organic molecule
Emp. Form.:
C28H22N4O5S
Mol. Mass.:
526.563
SMILES:
CC(=O)NS(=O)(=O)c1ccc(cc1)N1C(=O)\C(=C/c2cn(C(C)=O)c3ccccc23)N=C1c1ccccc1 |c:33|
Structure:
Search PDB for entries with ligand similarity: