Reaction Details Report a problem with these data
Target
Fibroblast growth factor 2
Ligand
BDBM50144520
Substrate
n/a
Meas. Tech.
ChEMBL_70634 (CHEMBL678690)
Kd
>800000±n/a nM
Citation
 Liu, L; Ping Li, C; Cochran, S; Ferro, V Application of the four-component Ugi condensation for the preparation of sulfated glycoconjugate libraries. Bioorg Med Chem Lett 14:2221-6 (2004) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 2
Synonyms:
Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2
Type:
Protein
Mol. Mass.:
30803.89
Organism:
Homo sapiens (Human)
Description:
P09038
Residue:
288
Sequence:
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
  
Inhibitor
Name:
BDBM50144520
Synonyms:
CHEMBL308715 | Sodium sulfated glycoconjugate derivative
Type:
Small organic molecule
Emp. Form.:
C27H30N2O19S4
Mol. Mass.:
814.791
SMILES:
[O-]S(=O)(=O)OC1OC(C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O)C(=O)N(Cc1ccccc1)C(C(=O)NC1CCCCC1)c1ccccc1
Structure:
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