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Target
D(2) dopamine receptor
Ligand
BDBM50180290
Substrate
n/a
Meas. Tech.
ChEMBL_329486 (CHEMBL861746)
Ki
>750±n/a nM
Citation
 Leopoldo, M; Lacivita, E; De Giorgio, P; Colabufo, NA; Niso, M; Berardi, F; Perrone, R Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands for visualization of brain dopamine D3 receptors. J Med Chem 49:358-65 (2006) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50180290
Synonyms:
CHEMBL202762 | N-[4-[4-(5-methoxy-2-benzoxazolyl)piperazin-1-yl]butyl]-7-methoxy-2-benzofurancarboxamide
Type:
Small organic molecule
Emp. Form.:
C26H30N4O5
Mol. Mass.:
478.5402
SMILES:
COc1ccc2oc(nc2c1)N1CCN(CCCCNC(=O)c2cc3cccc(OC)c3o2)CC1
Structure:
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