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Target
M-phase inducer phosphatase 1
Ligand
BDBM50197854
Substrate
n/a
Meas. Tech.
ChEMBL_435185 (CHEMBL904571)
IC50
5100±n/a nM
Citation
 Brault, L; Denancé, M; Banaszak, E; El Maadidi, S; Battaglia, E; Bagrel, D; Samadi, M Synthesis and biological evaluation of dialkylsubstituted maleic anhydrides as novel inhibitors of Cdc25 dual specificity phosphatases. Eur J Med Chem 42:243-7 (2007) [PubMed]  Article 
Target
Name:
M-phase inducer phosphatase 1
Synonyms:
CDC25A | Dual specificity phosphatase (Cdc25A) | Dual specificity phosphatase Cdc25A | M-phase inducer phosphatase 1 | MPIP1_HUMAN | phosphatase Cdc25
Type:
Protein
Mol. Mass.:
59090.18
Organism:
Homo sapiens (Human)
Description:
P30304
Residue:
524
Sequence:
MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
  
Inhibitor
Name:
BDBM50197854
Synonyms:
3-(4-heptadecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)propanoicacid | CHEMBL228419
Type:
Small organic molecule
Emp. Form.:
C24H40O5
Mol. Mass.:
408.5714
SMILES:
CCCCCCCCCCCCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O |c:17|
Structure:
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