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Target
Estrogen receptor beta
Ligand
BDBM50154080
Substrate
n/a
Meas. Tech.
ChEMBL_530438 (CHEMBL973102)
IC50
39±n/a nM
Citation
 Luan, F; Liu, HT; Ma, WP; Fan, BT Classification of estrogen receptor-beta ligands on the basis of their binding affinities using support vector machine and linear discriminant analysis. Eur J Med Chem 43:43-52 (2008) [PubMed]  Article 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM50154080
Synonyms:
2-(3-Fluoro-4-hydroxy-phenyl)-benzooxazol-6-ol | 2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol-6-ol | CHEMBL189002
Type:
Small organic molecule
Emp. Form.:
C13H8FNO3
Mol. Mass.:
245.2059
SMILES:
Oc1ccc2nc(oc2c1)-c1ccc(O)c(F)c1
Structure:
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