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Target
Interstitial collagenase
Ligand
BDBM50286566
Substrate
n/a
Meas. Tech.
ChEBML_101756
Ki
>10000±n/a nM
Citation
 Esser, CK; Kopka, IE; Durette, PL; Harrison, RK; Niedzwiecki, LM; Izquierdo-Martin, M; Stein, RL; Hagmann, WK Inhibition of matrix metalloproteinases by N-carboxyalkyl peptides containing extended alkyl residues At P1' Bioorg Med Chem Lett 5:539-542 (1995)    Article 
Target
Name:
Interstitial collagenase
Synonyms:
CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1)
Type:
Enzyme
Mol. Mass.:
54010.26
Organism:
Homo sapiens (Human)
Description:
P03956
Residue:
469
Sequence:
MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
  
Inhibitor
Name:
BDBM50286566
Synonyms:
(R)-2-[(S)-1-((S)-4-Guanidino-1-phenylcarbamoyl-butylcarbamoyl)-nonylamino]-propionic acid | CHEMBL150628
Type:
Small organic molecule
Emp. Form.:
C25H42N6O4
Mol. Mass.:
490.6388
SMILES:
CCCCCCCC[C@H](N[C@H](C)C(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1ccccc1
Structure:
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