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Target
Cytosol aminopeptidase
Ligand
BDBM50024602
Substrate
n/a
Meas. Tech.
ChEMBL_98405 (CHEMBL706602)
Ki
1200±n/a nM
Citation
 Giannousis, PP; Bartlett, PA Phosphorus amino acid analogues as inhibitors of leucine aminopeptidase. J Med Chem 30:1603-9 (1987) [PubMed]  Article 
Target
Name:
Cytosol aminopeptidase
Synonyms:
AMPL_HUMAN | Aminopeptidase | LAP3 | LAPEP | Leucine aminopeptidase | PEPS
Type:
PROTEIN
Mol. Mass.:
56171.75
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507539
Residue:
519
Sequence:
MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFDKLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKENIRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGSGDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWIEEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQVDNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHLDIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
  
Inhibitor
Name:
BDBM50024602
Synonyms:
1-Ammonium-2-methyl-propane-1-phosphonic acid anion | 1-amino-2-methylpropylphosphonic acid | CHEMBL41544
Type:
Small organic molecule
Emp. Form.:
C4H12NO3P
Mol. Mass.:
153.1167
SMILES:
CC(C)C([NH3+])P(O)([O-])=O
Structure:
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