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Target
Somatostatin receptor type 2
Ligand
BDBM50064770
Substrate
n/a
Meas. Tech.
ChEMBL_200366 (CHEMBL805714)
Ki
615±n/a nM
Citation
 Yang, L; Guo, L; Pasternak, A; Mosley, R; Rohrer, S; Birzin, E; Foor, F; Cheng, K; Schaeffer, J; Patchett, AA Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. J Med Chem 41:2175-9 (1998) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50064770
Synonyms:
1'N-[1-(4-aminobutylcarbamoyl)-2-(1H-3-indolyl)ethyl]spiro[1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide | CHEMBL302567
Type:
Small organic molecule
Emp. Form.:
C29H35N5O2
Mol. Mass.:
485.6205
SMILES:
NCCCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(CC1)C=Cc1ccccc21 |c:31|
Structure:
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