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Target
Somatostatin receptor type 3
Ligand
BDBM50064774
Substrate
n/a
Meas. Tech.
ChEMBL_200506 (CHEMBL803851)
Ki
3614±n/a nM
Citation
 Yang, L; Guo, L; Pasternak, A; Mosley, R; Rohrer, S; Birzin, E; Foor, F; Cheng, K; Schaeffer, J; Patchett, AA Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. J Med Chem 41:2175-9 (1998) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50064774
Synonyms:
1'N-[1-(3-aminomethylcyclohexylmethylcarbamoyl)-2-(1H-3-indolyl)-(1S)-ethyl]spiro[1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide | CHEMBL305279
Type:
Small organic molecule
Emp. Form.:
C33H41N5O2
Mol. Mass.:
539.7109
SMILES:
NCC1CCCC(CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(CC2)C=Cc2ccccc32)C1 |c:34|
Structure:
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