Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50389435
Substrate
n/a
Meas. Tech.
ChEMBL_832032 (CHEMBL2065328)
Ki
74.1±n/a nM
Citation
 Kozaka, T; Uno, I; Kitamura, Y; Miwa, D; Ogawa, K; Shiba, K Syntheses and in vitro evaluation of decalinvesamicol analogues as potential imaging probes for vesicular acetylcholine transporter (VAChT). Bioorg Med Chem 20:4936-41 (2012) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50389435
Synonyms:
CHEMBL2064617
Type:
Small organic molecule
Emp. Form.:
C21H31NO
Mol. Mass.:
313.4769
SMILES:
OC1C[C@@H]2CCCC[C@H]2CC1N1CCC(CC1)c1ccccc1 |r|
Structure:
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