Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM60193
Substrate
n/a
IC50
246.39±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM60193
Synonyms:
(2Z)-2-[[1-(4-methoxyphenyl)-2,6-dimethyl-4-pyridin-1-iumyl]methylidene]-3-methyl-1,3-benzothiazole;iodide | (2Z)-2-[[1-(4-methoxyphenyl)-2,6-dimethyl-pyridin-1-ium-4-yl]methylene]-3-methyl-1,3-benzothiazole;iodide | (2Z)-2-[[1-(4-methoxyphenyl)-2,6-dimethyl-pyridin-1-ium-4-yl]methylidene]-3-methyl-1,3-benzothiazole;iodide | (2Z)-2-[[1-(4-methoxyphenyl)-2,6-dimethylpyridin-1-ium-4-yl]methylidene]-3-methyl-1,3-benzothiazole;iodide | MLS001011153 | SMR000353120 | cid_16196223
Type:
Small organic molecule
Emp. Form.:
C23H23N2OS
Mol. Mass.:
375.506
SMILES:
COc1ccc(cc1)-[n+]1c(C)cc(\C=C2/Sc3ccccc3N2C)cc1C
Structure:
Search PDB for entries with ligand similarity: