Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97182
Substrate
n/a
IC50
358.39±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97182
Synonyms:
3-(4-methoxy-2-methyl-phenyl)-N-veratryl-benzofuran-7-carboxamide | MLS003120612 | N-[(3,4-dimethoxyphenyl)methyl]-3-(4-methoxy-2-methyl-phenyl)-1-benzofuran-7-carboxamide | N-[(3,4-dimethoxyphenyl)methyl]-3-(4-methoxy-2-methylphenyl)-1-benzofuran-7-carboxamide | N-[(3,4-dimethoxyphenyl)methyl]-3-(4-methoxy-2-methylphenyl)-7-benzofurancarboxamide | SMR001289998 | cid_46943517
Type:
Small organic molecule
Emp. Form.:
C26H25NO5
Mol. Mass.:
431.4804
SMILES:
COc1ccc(-c2coc3c(cccc23)C(=O)NCc2ccc(OC)c(OC)c2)c(C)c1
Structure:
Search PDB for entries with ligand similarity: