Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM31048
Substrate
n/a
Ki
151.7±n/a nM
Comments
PDSP_258
Citation
 Lahti, RA; Evans, DL; Stratman, NC; Figur, LM Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: possible therapeutic implications. Eur J Pharmacol 236:483-6 (1993) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM31048
Synonyms:
AJ119,(+) | MLS000069646 | N-(6-propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester | OXIBENDAZOLE | SMR000058208 | cid_4622 | methyl N-(6-propoxy-1H-benzimidazol-2-yl)carbamate
Type:
Small organic molecule
Emp. Form.:
C12H15N3O3
Mol. Mass.:
249.2658
SMILES:
CCCOc1ccc2nc(NC(=O)OC)[nH]c2c1
Structure:
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