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Target
Metallo-beta-lactamase type 2
Ligand
BDBM26116
Substrate
n/a
Meas. Tech.
ChEMBL_1669140 (CHEMBL4019028)
IC50
3030±n/a nM
Citation
 Chen, AY; Thomas, PW; Stewart, AC; Bergstrom, A; Cheng, Z; Miller, C; Bethel, CR; Marshall, SH; Credille, CV; Riley, CL; Page, RC; Bonomo, RA; Crowder, MW; Tierney, DL; Fast, W; Cohen, SM Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-?-lactamase-1. J Med Chem 60:7267-7283 (2017) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase type 2
Synonyms:
B2 metallo-beta-lactamase | BLA-IMP | BLAB_SERMA | Beta-lactamase type II | IMP-1 | Metallo-beta-lactamase type II
Type:
undefined
Mol. Mass.:
27125.88
Organism:
Serratia marcescens
Description:
P52699
Residue:
246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPSKPSN
  
Inhibitor
Name:
BDBM26116
Synonyms:
CHEMBL284104 | Dipicolinate | pyridine carboxylate, 6d | pyridine-2,6-dicarboxylic acid
Type:
Small organic molecule
Emp. Form.:
C7H5NO4
Mol. Mass.:
167.1189
SMILES:
OC(=O)c1cccc(n1)C(O)=O
Structure:
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