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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50357993
Substrate
n/a
Meas. Tech.
ChEMBL_786344 (CHEMBL1920540)
Ki
6281±n/a nM
Citation
 Zajdel, P; Marciniec, K; Maslankiewicz, A; Paluchowska, MH; Satala, G; Partyka, A; Jastrzebska-Wiesek, M; Wróbel, D; Wesolowska, A; Duszynska, B; Bojarski, AJ; Pawlowski, M Arene- and quinoline-sulfonamides as novel 5-HT7 receptor ligands. Bioorg Med Chem 19:6750-9 (2011) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52852.05
Organism:
Rattus norvegicus (rat)
Description:
Rat cortex membranes 5-HT2A receptors.
Residue:
471
Sequence:
MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
  
Inhibitor
Name:
BDBM50357993
Synonyms:
CHEMBL1917359
Type:
Small organic molecule
Emp. Form.:
C24H35N3O2S
Mol. Mass.:
429.619
SMILES:
CCN(CCCCN1CCC2CCCCC2C1)S(=O)(=O)c1cccc2cccnc12
Structure:
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