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Target
Pancreatic alpha-amylase
Ligand
BDBM50401979
Substrate
n/a
Meas. Tech.
ChEMBL_886576 (CHEMBL2215736)
IC50
22960±n/a nM
Citation
 Patil, VS; Nandre, KP; Ghosh, S; Rao, VJ; Chopade, BA; Bhosale, SV; Bhosale, SV Synthesis and glycosidase inhibitory activity of novel (2-phenyl-4H-benzopyrimedo[2,1-b]-thiazol-4-yliden)acetonitrile derivatives. Bioorg Med Chem Lett 22:7011-4 (2012) [PubMed]  Article 
Target
Name:
Pancreatic alpha-amylase
Synonyms:
1,4-alpha-D-glucan glucanohydrolase | AMY2 | AMYP_PIG | Pancreatic α-amylase | Pancreatic α-amylase
Type:
Protein
Mol. Mass.:
57088.07
Organism:
Sus scrofa (Pig)
Description:
P00690
Residue:
511
Sequence:
MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPPNENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGSGAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGLLDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAGSRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWARNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQPFANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL
  
Inhibitor
Name:
BDBM50401979
Synonyms:
CHEMBL2207948
Type:
Small organic molecule
Emp. Form.:
C18H11N3S
Mol. Mass.:
301.365
SMILES:
N#C\C=C1/C=C(N=C2Sc3ccccc3N12)c1ccccc1 |c:4,t:6|
Structure:
Search PDB for entries with ligand similarity: