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Target
Putative dihydropicolinate synthase
Ligand
BDBM26116
Substrate
n/a
Meas. Tech.
ChEBML_54082
IC50
400000±n/a nM
Citation
 Couper, L; McKendrick, JE; Robins, DJ; Chrystal, EJ Pyridine and piperidine derivatives as inhibitors of dihydrodipicolinic acid synthase, a key enzyme in the diaminopimelate pathway to l-lysine Bioorg Med Chem Lett 4:2267-2272 (1994)    Article 
Target
Name:
Putative dihydropicolinate synthase
Synonyms:
Dihydrodipicolinate synthase
Type:
PROTEIN
Mol. Mass.:
32147.51
Organism:
Streptomyces coelicolor
Description:
ChEMBL_54076
Residue:
298
Sequence:
MSETRKPWHGVIVATSLPFDDDLSVDFGAYGESVAHLAAQGMHGVAPNGSLGEYQTLTYEERDRVVETAVANAPEGFTVMPGVGAYGGREAERHARFAKDAGCQAVMCLPPNAYRADDRAVLQHFERVASVGLPVTAYNNPIDTKVDLRPDLLAKLHAEGYIVGVKEFSGDVRRCYEISELAPGLDLMIGTDDTVLEVALAGAKGWVAGYPQVFPRACLALYEASVRGDLEAALPLYRQLHPVLRWDSKTEFVQAIKLGQELTGRRGGPCRPPRQPLAPETEAVVRAATQALVDAGVN
  
Inhibitor
Name:
BDBM26116
Synonyms:
CHEMBL284104 | Dipicolinate | pyridine carboxylate, 6d | pyridine-2,6-dicarboxylic acid
Type:
Small organic molecule
Emp. Form.:
C7H5NO4
Mol. Mass.:
167.1189
SMILES:
OC(=O)c1cccc(n1)C(O)=O
Structure:
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