Reaction Details Report a problem with these data
Target
Glandular kallikrein
Ligand
BDBM50010063
Substrate
n/a
Meas. Tech.
ChEMBL_1342913 (CHEMBL3259188)
Ki
4110±n/a nM
Citation
 Tidwell, RR; Geratz, JD; Dann, O; Volz, G; Zeh, D; Loewe, H Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases. J Med Chem 21:613-23 (1978) [PubMed]  Article 
Target
Name:
Glandular kallikrein
Synonyms:
KLK_PIG | Tissue kallikrein
Type:
PROTEIN
Mol. Mass.:
26710.38
Organism:
Sus scrofa
Description:
ChEMBL_108296
Residue:
242
Sequence:
APPIQSRIIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENENTAQFFGVTADFPHPGFNLSLLKHTKADGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDFEFPDEIQCVQLTLLQNTFCAAHPKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHTPCGSANKPSIYTKLIFYLDWINDTITENP
  
Inhibitor
Name:
BDBM50010063
Synonyms:
CHEMBL1233459
Type:
Small organic molecule
Emp. Form.:
C21H18N6O
Mol. Mass.:
370.4072
SMILES:
NC(=N)c1ccc(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=N)cc1
Structure:
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