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Target
Bromodomain testis-specific protein [27-133]
Ligand
BDBM528580
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
31.0±n/a nM
Citation
 Pham, SM; Chakravarty, S; Kankanala, J; Chen, J; Nayak, AK; Barde, A Substituted 1,6-dihydropyridinones and 1,2-dihydroisoquinolinones as bet inhibitors US Patent  US11192900 Publication Date 12/7/2021 
Target
Name:
Bromodomain testis-specific protein [27-133]
Synonyms:
BRDT | BRDT-1 | BRDT_HUMAN | Bromodomain testis-specific protein (BD1, aa 27-133)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12808.37
Organism:
Homo sapiens (Human)
Description:
Q58F21[27-133]
Residue:
107
Sequence:
RLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQM
  
Inhibitor
Name:
BDBM528580
Synonyms:
US11192900, Compound 3 | US11192900, Example S-10
Type:
Small organic molecule
Emp. Form.:
C21H19F2N3O4S
Mol. Mass.:
447.455
SMILES:
CNc1cc(cn(C)c1=O)-c1cc(NS(=O)(=O)C=C)ccc1Oc1ccc(F)cc1F
Structure:
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