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Target
Trace amine-associated receptor 1
Ligand
BDBM250359
Substrate
n/a
Meas. Tech.
Human TAAR1 assay
EC50
37.7±n/a nM
Citation
 Galley, G; Hoener, M; Norcross, R; Pflieger, P Morpholine derivative US Patent  US11312711 Publication Date 4/26/2022 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM250359
Synonyms:
US10501411, Example 269 | US11312711, Example 3 | US11697636, Example 269 | US9452980, 269
Type:
Small organic molecule
Emp. Form.:
C18H18F3N3O3
Mol. Mass.:
381.349
SMILES:
FC(F)(F)COc1ccc(cn1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r|
Structure:
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