Reaction Details Report a problem with these data
Target
POU domain, class 5, transcription factor 1
Ligand
BDBM306794
Substrate
n/a
Meas. Tech.
OCT3 inhibitory activity
IC50
25300±n/a nM
Citation
 Yamashita, H; Suzuki, N OCT3 activity inhibitor containing imidazopyridine derivative as active component, and OCT3 detection agent US Patent  US10149840 Publication Date 12/11/2018 
Target
Name:
POU domain, class 5, transcription factor 1
Synonyms:
OCT3 | OCT4 | OTF-3 | OTF3 | Oct-3 | Oct-4 | Octamer-binding protein 3 | Octamer-binding protein 4 | Octamer-binding transcription factor 3 | PO5F1_HUMAN | POU5F1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38567.64
Organism:
Homo sapiens (Human)
Description:
Q01860
Residue:
360
Sequence:
MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
  
Inhibitor
Name:
BDBM306794
Synonyms:
US10149840, Compound SR-4229 | US10149840, Series Number 41
Type:
Small organic molecule
Emp. Form.:
C18H18N6OS
Mol. Mass.:
366.44
SMILES:
CCOc1ccccc1-n1nnnc1SCc1cn2cc(C)ccc2n1
Structure:
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