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Target
Neuraminidase
Ligand
BDBM575125
Substrate
n/a
Meas. Tech.
Assessing Antiviral Activity Against Influenza
IC50
1787±n/a nM
Citation
 Remiszewski, S; Chiang, LW; Murphy, EA; Sun, Q; Kayser, F; Fink, SJ Broad spectrum antiviral compositions and methods US Patent  US11459321 Publication Date 10/4/2022 
Target
Name:
Neuraminidase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
50125.13
Organism:
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Description:
A0A1C9ZU71
Residue:
454
Sequence:
MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNSTWVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSSGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKIFKIEKGRVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIWDPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKTIWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
  
Inhibitor
Name:
BDBM575125
Synonyms:
US11459321, Example 65
Type:
Small organic molecule
Emp. Form.:
C25H22N6OS
Mol. Mass.:
454.547
SMILES:
Cc1nnc(o1)-c1ccc2CCN(Cc2c1)c1ncc(Cc2ccc(cc2)-n2cccn2)s1
Structure:
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