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Target
Chromatin remodeling regulator CECR2 [424-538]
Ligand
BDBM310905
Substrate
n/a
Meas. Tech.
CECR2 TR-FRET Binding Assay
IC50
36.0±n/a nM
Citation
 Albrecht, BK; Bellon, SF; Burdick, DJ; Cote, A; Crawford, T; Dakin, LA; Hsiao-Wei Tsui, V; Hewitt, MC; LeBlanc, Y; Magnuson, SR; Nasveschuk, CG; Romero, AF; Tang, Y; Taylor, AM; Wang, S Therapeutic compounds and uses thereof US Patent  US10150767 Publication Date 12/11/2018 
Target
Name:
Chromatin remodeling regulator CECR2 [424-538]
Synonyms:
CECR2 | CECR2 (aa 424-538) | CECR2_HUMAN | Cat eye syndrome critical region protein 2 [424-538] | KIAA1740
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13747.10
Organism:
Homo sapiens (Human)
Description:
Q9BXF3[424-538]
Residue:
115
Sequence:
MREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKH
  
Inhibitor
Name:
BDBM310905
Synonyms:
2-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4H-1,4-benzoxazin-3-one | US10150767, Example 16
Type:
Small organic molecule
Emp. Form.:
C17H15N3O3
Mol. Mass.:
309.3193
SMILES:
CC1Oc2cc(ccc2NC1=O)-c1cn(C)c(=O)c2[nH]ccc12
Structure:
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