Reaction Details Report a problem with these data
Target
Bromodomain-containing protein 9 [133-239]
Ligand
BDBM621666
Substrate
n/a
Meas. Tech.
BRD9 Bromodomain TR-FRET Competition Binding Assay
IC50
<10±n/a nM
Citation
 Zhou, Q; Bocker, M; Millan, DS; Chan, HM; Soares, L; Netherton, MR; Ruppel, SK; Yang, Z; Lowe, JT; Brucelle, F Methods and compounds for treating disorders US Patent  US11773085 Publication Date 10/3/2023 
Target
Name:
Bromodomain-containing protein 9 [133-239]
Synonyms:
BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 (BRD9)(133-239)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12383.34
Organism:
Homo sapiens (Human)
Description:
aa 133-239
Residue:
107
Sequence:
PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
  
Inhibitor
Name:
BDBM621666
Synonyms:
N-[[2,6-dimethoxy-4-(2-methyl-1-oxo-2,7-naphthyridin-4-yl)phenyl]methyl]-N-methylmethanesulfonamide | US11773085, Compound B38
Type:
Small organic molecule
Emp. Form.:
C20H23N3O5S
Mol. Mass.:
417.479
SMILES:
COc1cc(cc(OC)c1CN(C)S(C)(=O)=O)-c1cn(C)c(=O)c2cnccc12
Structure:
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